01 · HAEMODYNAMICS
Flow meets resistance.
Blood pressure can be thought of as flow through a vascular system against resistance. Cardiac output reflects heart rate and stroke volume; vascular tone contributes to systemic resistance. A number gains meaning from the person’s baseline, time course and perfusion context.
- Preload: ventricular filling before contraction.
- Afterload: the resistance against ejection.
- Contractility: intrinsic force generation at a given loading state.
Retrieve: Explain why a pressure reading cannot substitute for a description of perfusion.
02 · HYPERTENSION
Pressure is a risk signal.
Hypertension is a sustained pattern, not merely one isolated reading. The learning framework connects vascular resistance, target-organ vulnerability and the importance of measurement context. Exam questions often distinguish a screening value from a confirmed pattern.
- Think measurement quality and repeat context.
- Think cumulative vascular burden.
- Think secondary causes as a structured possibility, not an automatic answer.
Retrieve: Why does “sustained pattern” matter more than a single elevated number?
03 · ISCHAEMIA
Supply and demand can diverge.
Myocardial ischaemia is a mismatch between oxygen supply and demand. Coronary anatomy matters, but so do rate, blood pressure, oxygen content and physiological stress. A vignette becomes easier when you identify the mechanism it is asking you to prioritise.
- Supply relates to coronary flow and oxygen content.
- Demand rises with factors such as rate, wall stress and contractile work.
- Time course and symptoms are part of interpretation.
Retrieve: Give two broad influences on supply and two on demand.
04 · HEART FAILURE
A syndrome of pump and pressure.
Heart failure is a clinical syndrome in which cardiac structure or function impairs the ability to meet circulatory demands without elevated filling pressures. The exam skill is to connect symptoms, congestion, perfusion and underlying mechanism—not to memorise one rigid picture.
- Systolic and diastolic function describe different aspects of performance.
- Congestion and low output are physiological themes, not interchangeable labels.
- Underlying cause and chronology shape interpretation.
Retrieve: Contrast congestion with low-output physiology at a concept level.
05 · VALVULAR DISEASE
Obstruction or leakage changes the load.
Stenosis obstructs forward flow; regurgitation permits backward flow. Both alter chamber loading over time and produce characteristic haemodynamic consequences. For exams, connect the lesion to the direction of flow and then to the chamber adapting to that burden.
- Stenosis commonly creates pressure loading upstream of an obstruction.
- Regurgitation commonly creates volume loading from reverse flow.
- Timing and location of a murmur are clues within a wider map.
Retrieve: Why are stenosis and regurgitation different loading problems?
06 · RHYTHM
Electrical order creates mechanical order.
Normal rhythm depends on organised impulse formation and conduction. Arrhythmia questions reward a structured approach: rate, regularity, relation of atrial and ventricular activity, and clinical context. A tracing is evidence to interpret, not a diagnosis without context.
- Rate asks how fast.
- Regularity asks how evenly impulses are spaced.
- Atrial–ventricular relationship asks whether electrical events remain coordinated.
Retrieve: Name the three first descriptors for an exam ECG rhythm question.